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Science & Reproduction

Science

Written by Sophie Goodchild

No significant differences found in rates of embryos suitable for transfer and live birth rates between conventional IVF and ICSI in non-male factor cycles undergoing PGT-A....

5 Feb, 2024

4 min read

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Embryo transfer

The Dutch multicenter randomised "Three or Five" (ToF) trial found that while transferring blastocyst on day 5 leads to higher live birth rates in fresh transfers and lower pregnancy loss rates than cleavage-stage transfers, cumulative live birth rates were similar, an...

Written by Paola Vigano’ and Alessio Paffoni

3 Dec, 2024

3 min read

Written by Fiona MacRae

Early pregnancy
Women who face a lot of adversity around the time of conception are more likely to have elevated cortisol and reduced growth in early pregnancy. Findings from a new cohort study emphasise the need to identify vulnerable patients as early as possible....

12 Nov, 2024

4 min read

Written by George Liperis

Poor ovarian response
A multi-centre randomised controlled trial (RCT) has found intraovarian PRP injections do not enhance mature oocyte yield or other embryological or clinical parameters in women less than 38 years old with a history of POR....

7 Nov, 2024

4 min read

Written by Mina Mincheva

Fertility preservation
A scoping review highlights key progress made over the last 30 years for preserving and restoring male fertility using prepubertally cryopreserved testicular tissue. Risks of reintroducing malignant cells, introducing epigenetic aberrations and the need for consensus o...

29 Oct, 2024

6 min read

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Annual Meeting Science

Interview with Heidi Mertes

5 Aug, 2024

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Interview with Rod Mitchell

Annual Meeting Science
More than 3,000 boys around the world have had testicular tissue cryopreserved to protect their fertility.  Professor Rod Mitchell, of the University of Edinburgh, spoke to Fiona MacRae about how close we are to using that tissue to allow them to father ...

5 Aug, 2024

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Interview with Agnès Arbat

Annual Meeting Science
Dr Agnès Arbat, of Oxolife, a biotech that has developed an oral non-hormonal drug to increase implantation rates, talks through the phase 2 results.  She tells Fiona MacRae that the compound, which acts directly on the endometrium, may also help treat i...

5 Aug, 2024

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Interview with Madelon van Wely

Annual Meeting Science
Cochrane reviews are regarded as a gold standard in evidence-based healthcare. But how do Cochrane’s editors identify problematic studies, what are the challenges in identifying the best evidence, and how can automation such as AI help? These questions a...

5 Aug, 2024

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ESHRE Workshop Science

Interview with Sharmila Rudrappa

23 May, 2024

0 min listen

Interview with Dr Aleksej Stevanovic

Science
During a Campus meeting in March on environmental quality in the lab, Aleksej Stevanovic gave a presentation on temperature control. Here Dr Stevanovic, junior deputy coordinator SIG Safety and Quality in IVF, talks to Sophie Goodchild from Focus on Reproduction includ...

21 Mar, 2024

11 min listen

Interview with Professor Maria José De los Santos Molina

Science
Vitrification has been a game-changer in fertility preservation. However, there is still room for improvement with oocyte freezing. Professor Maria José De los Santos Molina, from IVIRMA Valencia, outlines methods to increase the survival rate including altering the la...

6 Dec, 2023

10 min listen