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CHILD DEVELOPMENT AFTER ART

Growth patterns in ART children found different from those in naturally conceived

A large cohort study has shown that children conceived by ART are smaller at the time of delivery, experience a rapid catch-up growth, but are largely similar in height and weight to naturally conceived children at school age.

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COUNSELLING

Counselling faces a minefield of hazards in donor conception today

The availability of genealogy services today and the non-guarantee of donor anonymity has raised new questions for counsellors in donor conception. A Campus meeting in January explored the priorities, especially for the children born.

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CAMPUS MEETING

New concepts and strategies aiming to improve success rates in ART

At a time when European pregnancy rates have plateau’d a well attended Campus meeting in January reviewed new (and old) concepts in the planning and strategies of treatments to improve success rates. The debates continue, some after many years.

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FERTILITY PRESERVATION

Patient age the determinant of success in elective fertility preservation for women - and men

A well attended online Campus meeting in December heard that outcome from elective oocyte cryopreservation depends on the number of MII oocytes retrieved, and that varies with age. Older age also brings more neonatal risks for mother and baby.

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ANALGESICS

New review of analgesics in pregnancy advises minimum dose for shortest time

Review of over-the-counter analgesics taken in pregnancy finds their prevalent use ‘high’ and increasing, with knowledge gaps apparent relating to fetal exposure and offspring health.

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COVID-19

Markers of sperm quality found adversely affected by COVID-19

An experimental study which measured markers of inflammation and oxidative stress in the sperm cells of men infected with COVID-19 found significantly higher levels than in healthy controls. Experts urge caution in interpreting results.

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COVID-19 VACCINE

A precautionary edge to ESHRE’s statement on COVID-19 vaccination in and before pregnancy

A recent statement from ESHRE’s COVID-19 working group, also evident in the vaccines’ product information, notes limited data on vaccination in pregnancy and none before conception with assisted reproduction. Eligibility for COVID-19 vaccination in and before pregnancy so far rests on an individual assessment of risks and benefits.

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SPERM DNA

An emerging case for measuring sperm DNA damage before ART

While assays for sperm DNA remain controversial in their association with pregnancy, a new opinion paper in Human Reproduction makes the case for screening before ART based not on improving success rates but on minimising adverse health outcomes in the children conceived.

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TROPHECTODERM BIOPSY

Risk of hypertensive disorders of pregnancy linked to trophectoderm biopsy in new study

A large single-centre study has found a two-fold higher risk of pregnancy-related hypertension following blastocyst biopsy and frozen transfer than in non-biopsied controls. Dublin embryologist Joyce Leyden, an ESHRE young ambassador, reports.

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IMPLANTATION FAILURE

Recurrent implantation failure found to be ‘rare’ in euploid embryo transfers

Large retrospective study of more than 4000 euploid embryo transfers finds very high implantation rates after each of three successive FETs. Recurrent implantation failure likely to be embryonic and not endometrial in its origin, propose investigators.

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