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COVID-19 VACCINE

A precautionary edge to ESHRE’s statement on COVID-19 vaccination in and before pregnancy

A recent statement from ESHRE’s COVID-19 working group, also evident in the vaccines’ product information, notes limited data on vaccination in pregnancy and none before conception with assisted reproduction. Eligibility for COVID-19 vaccination in and before pregnancy so far rests on an individual assessment of risks and benefits.

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FUNDING OF ART

Safer outcomes from state-funded fertility treatments

Large Canadian study finds state-funded ART linked to a higher rate of SET and a lower risk of adverse neonatal outcomes for mother and baby.

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ERRORS IN ART 2

Quality management and reducing the risks of errors in the IVF lab

A well attended Campus meeting in November heard how quality management systems and a willingness to discuss all mishaps and near-misses reduce the risks of errors in the ART clinic.

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CANCER RISK

Risk of ovarian cancer is not associated with ART in long-term cohort study

A study which cross-linked more than 30,000 Dutch ART patients to the national cancer registry with follow-up over a mean of 24 years found they had a greater risk of ovarian cancer than women in the general population but no greater risk than in an untreated group of sub-fertile women.

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IMPLANTATION FAILURE

Recurrent implantation failure found to be ‘rare’ in euploid embryo transfers

Large retrospective study of more than 4000 euploid embryo transfers finds very high implantation rates after each of three successive FETs. Recurrent implantation failure likely to be embryonic and not endometrial in its origin, propose investigators.

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GENOMIC MEDICINE

The expanding role of genomics in preconceptional ‘personalised’ medicine

A well attended online Campus course staged by the SIG Reproductive Genetics heard that the expansion of sequencing analysis is poised to push forward the development of cost-effective preconception tests able to identify several underlying genetic causes of infertility

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ERRORS IN ART 1

Mishaps and their prevention in the IVF lab

Although errors in the IVF lab are reportedly few, their consequences may be catastrophic for both patients and clinic. A well attended online Campus meeting in November heard how they may occur and how prevented.

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FERTILITY PRESERVATION

Patient age the determinant of success in elective fertility preservation for women - and men

A well attended online Campus meeting in December heard that outcome from elective oocyte cryopreservation depends on the number of MII oocytes retrieved, and that varies with age. Older age also brings more neonatal risks for mother and baby.

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COVID-19

ESHRE reaffirms its guidance for a COVID-free clinic

ESHRE’s COVID-19 working group hosted a session at this year’s Progress Educational Trust annual meeting to reveal striking differences between clinic activity during the first infection wave and the second. A strict protocol of triage and testing can keep fertility centres COVID-free.

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EUROPEAN IVF MONITORING

Just how does ART in Europe compare with ART in the USA and Australia?

Twenty years after its first data collection from European ART cycles, ESHRE’s IVF Monitoring Consortium has compared its cumulative findings with two other national registries – and found that Europe is the slowest on the uptake of new techniques.

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