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MALE INFERTILITY

Male infertility associated with raised risk of prostate cancer in large cohort study

A comprehensive registry study from Sweden involving more than 1.2 million fathers links a significantly higher risk of prostate cancer to male subfertility - but not to ICSI and IVF treatment.

NATURAL CONCEPTION

One in six couples conceive spontaneously after unsuccessful ART

A cohort study which followed-up more than 2000 IVF patients in a single fertility centre found that 17% conceived spontaneously after unsuccessful ART and 15% after successful treatment.

ESHRE JOURNALS

Another step forward for HROpen: all papers now searchable in PubMed index

Indexing of ESHRE's open access journal after only two years of publication is seen not just as 'empirical proof of our existence', but also as a key step on the way to an impact factor.

ART COMPLICATIONS

Pre-eclampsia now associated with trophectoderm biopsy

Following a flurry of studies suggesting maternal and neonatal complications in ART, a new cohort analysis finds a higher incidence of pre-eclampsia in pregnancies following PGT than without PGT.

CAESAREAN SECTION

Neonatal colonisation of bacteria affected by caesarean section

Findings from the largest ever study of the newborn microbiome offer the strongest evidence yet that children delivered vaginally carry different microbes from those delivered by caesarean section.

ART COMPLICATIONS

The epigenetic signature of ART fades away in adulthood

A longitudinal cohort study has found that the majority of epigenetic changes found in neonates and attributed to ART seem to be resolved later in life.

OOCYTE NUMBER

More is less, more is better: oocyte number and optimal IVF

Recent studies suggest that in fresh single IVF cycles optimum results can be achieved with as few as nine fertilised oocytes. This is in contrast to results in cumulative cycles, where the more oocytes, apparently, the better.

CAMPUS: SIG REPRODUCTIVE GENETICS

Non-invasive PGT-A: many questions remain before clinical application

More than 170 registrants attended a wide-ranging Campus meeting on the established and emerging techniques of aneuploidy testing and on the latest developments in genomic editing and mitochondrial transfer.

AIR POLLUTION

Ambient air pollution found unrelated to IVF outcomes

A cohort study involving more than 250,000 IVF cycles has found no correlation between treatment outcomes and low daily ambient levels of particulate matter and ozone.

BOOK REVIEW

A life of egalitarian principle and dogged determination

Our knowledge of Robert Edwards comes from a mix of anecdote, brief encounters, autobiographical snatches and occasional scholarly research. Now, his former student Roger Gosden has completed the first authorised biography of ESHRE's founder, reviewed here by Simon Brown, editor of Focus on Reproduction.