ESHRE 2019 promises another feast of science with 1854 abstract submissions, a hot invited programme now in place, and 16 precongress courses.

A recent study has found that most trials and meta-analyses in reproductive medicine are insufficiently powered to produce a meaningful indication of live birth rate. Is the base of evidence-based medicine robust enough?

With formalities now completed, ESHRE can report that a submission on actin-dependent chromosome cohesion in oocytes took the €50,000 award, while a far-reaching project on the effects of obesity on embryo metabolism - and the potential for correction in culture media - was selected for the €150,000 award.

HPV infection is common and long lasting, especially in men, and it may provide one explanation for some of what has so far been classified as 'unexplained' infertility.

As another meta-analysis finds only limited outcome benefit from frozen embryo transfers, US data indicate that 25% of all cycles in 2016 were freeze-all.

Sexual dysfunction is a common cause and consequence of infertility. Study results are patchy, but sexual problems may respond to discussion, cognitive behavioural therapy and medication.

Professor Chris Barratt, former editor of Molecular Human Reproduction and a former co-ordinator of the SIG Andrology, talks to Focus on Reproduction about preconceptional and in utero factors in the determination of male infertility and future general health.

ESHRE Chairman Roy Farquharson describes the outcome of a two-year strategic review which aims to enhance member support in five key areas of ESHRE activity.

Sexual disorders may be a cause and consequence of infertility, but evidence of their impact remains sketchy, and strategies to deal with them hindered by inconsistency and misinformation.

There is strong evidence of a fetal and even preconceptional origin to male reproductive and general health. A Campus meeting in March reviewed the evidence and underlined the importance of male infertility as a marker of future health.