Two studies find a sudden increase in the rate of stillbirth and neonatal death, which may, say their authors, be attributed to fewer hospitalisations during periods of lockdown.

Study of more than 600 euploid blastocysts finds mitochondrial DNA content does not correlate with female age and is not predictive of reproductive outcomes.

A little more cohort data helps nudge ovarian tissue freezing for medically indicated fertility preservation from the experimental towards the routine; live birth outcomes significantly affected by patient age.

A new complex modelling study forecasts steep declines in total fertility rate by the end of this century, with most of 195 countries analysed unable to maintain their population levels.

The largest study to compare the viability of vitrified and fresh sibling oocytes has reaffirmed their comparable efficacy, but only when the efficiency of the vitrification procedure – and oocyte loss at warming - are taken into account.

A review of findings from observational studies and meta-analyses concludes that maternal caffeine consumption is ‘reliably’ associated with several adverse outcomes of pregnancy. Pregnant women advised ‘to avoid caffeine’.

Despite reports of successful outcomes and new guidelines, doubts continue to prevail over the acceptability of transferring mosaic embryos.

A new report from a high-powered commission formed after gene-edited twins were born in China concludes that the editing technologies must be still be proven safe and effective before countries might approve their use in human embryos.

A study testing aneuploidy in more than 3000 embryos derived from young egg donors and male partners whose ages extended beyond 50 years has failed to find any correlation between the prevalence of aneuploidy and paternal age.

A new cohort study from a national US database confirms that a lower risk of OHSS is associated with increasing use of GnRH antagonists and agonist trigger and a freeze-all approach to avoid immediate pregnancy.