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BMI

Obesity and IVF outcome: cohort study finds no effect of BMI on embryo ploidy

A retrospective cohort study has found no significant relationship between the ploidy status of IVF embryos and BMI, suggesting that an explanation for lower birth rates in obese patients lies elsewhere. This is the first report of another new writer recruit for Focus on Reproduction, Georgios Sigalos from Athens.*

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BEST OF ASRM & ESHRE

PGT-A for all? The debate goes on

After 25 years of controversy, and as the protagonists of a debate at our Best of ASRM & ESHRE meeting implied, consensus on the applicability of PGT-A for everyone seems as remote as ever. Efthymia Constantinou, Junior Deputy of ESHRE’s SIG Reproductive Genetics, offers her opinion from the IVF lab.

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DAY 2: BEST OF ASRM & ESHRE

Dual stimulation and PGT-A for all: more topics for debate

The menu of debates, back-to-back reviews and cutting-edge lectures to explore emerging themes continued on the second day of this Best of ASRM & ESHRE online meeting. Among themes explored were the emerging technique of double stimulation in predicted poor responders in IVF and the ever present conundrum of testing for aneuploidy in all patients.

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FERTILITY RATES

Baby boom is baby bust as post-lockdown birth rates take a dive

Birth rates in some Mediterranean countries have fallen dramatically in the first months of 2021, prompting speculation that ever-shrinking fecundity might signal economic hardship ahead. Can IVF help?

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MISCARRIAGE

Miscarriage: ‘The era of telling women to "just try again" is over’

A three-part report from international leaders in the medicine of early pregnancy calls for more consistency and focus in the diagnosis, investigation, treatment and management of miscarriage.

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FREEZE-ALL

Freeze-all ‘may be of no benefit’ in terms of ongoing pregnancy rate

A single-centre RCT involving more than 200 couples found ongoing pregnancy rate ‘significantly lower’ in the freeze-all group than in those following a conventional approach. Alessia Galimberti, one of our newly recruited writers, reports.*

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DAY 1: BEST OF ASRM & ESHRE

Recurrent implantation failure and elective oocyte freezing: hot topics open 2021 meeting

Almost 2000 members of ESHRE and ASRM (as well as many non-members) were registered for this seventh joint meeting of the two societies - indeed more attending virtually than had ever attended live.

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SEPTATE UTERUS

No evidence that septum resection improves reproductive outcomes

A randomised trial has confirmed earlier cohort study findings that septum resection in women with a septate uterus and a history of subfertility has no advantages over expectant management in improving live birth rates. Is there now any rationale behind surgery, ask the authors?

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DAY 3: BEST OF ASRM & ESHRE

Controversies in severe male factor infertility and in embryo transfer

On this third day of the Best of ASRM & ESHRE meeting the question of preconception factors associated with severe male factor was raised with new data from human and mouse models, while a debate on embryo transfer explored the preference, if any, of blastocyst over cleavage-stage transfer.

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IUI

Motile sperm count in the prediction of IUI success

The largest study of its kind reveals a ‘valuable’ sperm count threshold for the best chance of success in IUI, but warns that declines in pregnancy rate below this value are gradual and continuous.

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