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EU regulation of clinical practice

QUALITY MANAGEMENT

European regulation in ART still lags behind clinical progress

A Campus meeting in October covered a broad range of subjects each aiming to ensure a high-standard framework for ART. Among them was the EU's regulation of clinical practice and its systems of reprovigilance.

SIG EMBRYOLOGY VIENNA

Intrinsic and laboratory determinants of IVF success

Topics in this third review of embryology sessions from the oral presentation programme in Vienna include the timing of embryo transfer, extended embryo culture, paternal age, embryo arrest, and the effect of trophectoderm morphology grade - from Session 78.

Research

VIENNA ANNUAL MEETING

New priorities in fertility research

Vienna session organised by a 'priority setting partnership' for infertility unveils ten priorities for research in the four key areas: male infertility, female and unexplained infertility, assisted reproduction and the ethics of treatment.

VIENNA ANNUAL MEETING

Fertility treatment not associated with added long-term risk of ovarian cancer

There is now a long catalogue of inconclusive studies investigating an association between ART and risk of ovarian cancer. A large-scale multicentre analysis reported in Vienna concluded that nulliparity rather than ART is the likely explanation for any link. Results were described as 'reassuring'.

QUALITY MANAGEMENT

Quality management systems in ART are not just about compliance and legislation

A well attended Campus meeting in October heard that quality standards in an IVF centre - on embryo culture, traceability, risk management and evidence-based practice - depend on multiple factors, from the laboratory environment to the application of guidelines.

SIG EMBRYOLOGY VIENNA

New insights from time-lapse imaging

In this second review of embryology sessions in Vienna, we report from a selected oral communications session on time-lapse imaging. Six speakers presented their data on embryo assessment using various morphokinetic parameters to support their predictive value in embryo selection for transfer.

VIENNA ANNUAL MEETING

'Core outcome measures' for improving the reliability of fertility trials

Substantial heterogeneity exists in the reporting of outcomes of fertility trials, with inconsistencies in numerators, denominators and definitions making results difficult to interpret, compare and combine in meta-analyses. Jack Wilkinson presented the rationale for a core outcome set of measures for fertility trials on behalf of the Cochrane Gynaecology and Fertility Group and the COMMIT initiative in Vienna.

CAMPUS: SIG REPRODUCTIVE GENETICS

Non-invasive PGT-A: many questions remain before clinical application

More than 170 registrants attended a wide-ranging Campus meeting on the established and emerging techniques of aneuploidy testing and on the latest developments in genomic editing and mitochondrial transfer.

SIG EMBRYOLOGY VIENNA

Fertilisation in research and human IVF laboratories

Fertilisation was the subject of an invited session eloquently bringing to life its very beginnings. Two outstanding speakers reviewed events documented in research and clinical laboratories covering the fusion of gametes and the 24 hours thereafter.

VIENNA ANNUAL MEETING

Still caution over the prognostic value of testing for sperm DNA damage

Conventional semen analysis according to WHO manual parameters is limited, with no consideration of testis function or sperm quality. Madelon Van Wely of the Academic Medical Centre University of Amsterdam reviewed current evidence in support of sperm DNA fragmentation testing in ART.